Heteroplasmy variability in individuals with biparentally inherited mitochondrial DNA

Abstract
With very few exceptions, mitochondrial DNA (mtDNA) in humans is transmitted exclusively from mothers to their offspring, suggesting the presence of a strong evolutionary pressure favoring the exclusion of paternal mtDNA. We have recently shown strong evidence of paternal mtDNA transmission. In these rare situations, males exhibiting biparental mtDNA appear to be limited to transmitting just one of the mtDNA species to their offspring, while...
Paper Details
Title
Heteroplasmy variability in individuals with biparentally inherited mitochondrial DNA
Published Date
Feb 26, 2020
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