Heparan sulfate is a clearance receptor for aberrant extracellular proteins
Abstract
The accumulation of aberrant proteins leads to various neurodegenerative disorders. Mammalian cells contain several intracellular protein degradation systems, including autophagy and proteasomal systems, that selectively remove aberrant intracellular proteins. Although mammals contain not only intracellular but also extracellular proteins, the mechanism underlying the quality control of aberrant extracellular proteins is poorly understood. Here,...
Paper Details
Title
Heparan sulfate is a clearance receptor for aberrant extracellular proteins
Published Date
Feb 18, 2020
Journal
Volume
219
Issue
3
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