Relationship between fibrinogen level and its regulatory gene with Alzheimer’s disease and vascular dementia

ObjectiveSeveral investigations have shown that the level of fibrinogen (Fg) is associated with the susceptibility to dementia and is usually affected by polymorphisms in its gene. Our study aimed to investigate the relationship between Fg level and the fibrinogen β (FGB) −148C/T gene polymorphism in patients with Alzheimer’s disease (AD) and vascular dementia (VaD). MethodsThe study included 64 AD patients, 72 VaD patients, and 56 healthy...