A genetic analysis identifies a haplotype at adiponectin locus: Association with obesity and type 2 diabetes

Adiponectin is a prime determinant of the status of insulin resistance. Association studies between adiponectin ( ADIPOQ ) gene single nucleotide polymorphisms (SNPs) and metabolic diseases have been reported earlier. However, results are ambiguous due to apparent contradictions. Hence, we investigated (1) the association between ADIPOQ SNPs: −11377C/G, +10211T/G, +45T/G and +276G/T for the risk towards type 2 diabetes (T2D) and, (2)...