Mesenchymal stem cell-derived extracellular vesicles alone or in conjunction with a SDKP-conjugated self-assembling peptide improve a rat model of myocardial infarction

Volume: 524, Issue: 4, Pages: 903 - 909
Published: Apr 1, 2020
Abstract
The aim of this study was to investigate the cardiac repair effect of human bone marrow mesenchymal stromal cells-derived extracellular vesicles (MSC-EVs) after intramyocardial injection in free form or encapsulated within a self-assembling peptide hydrogel modified with SDKP motif, in a rat model of myocardial infarction (MI). MSC-EVs were isolated by ultracentrifuge and characterized for physical parameters and surface proteins. Furthermore,...
Paper Details
Title
Mesenchymal stem cell-derived extracellular vesicles alone or in conjunction with a SDKP-conjugated self-assembling peptide improve a rat model of myocardial infarction
Published Date
Apr 1, 2020
Volume
524
Issue
4
Pages
903 - 909
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