A comparison of the effects of the lipid-soluble CORM-2 and the water-soluble CORM-3 and CORM-A1 on platelet adhesion: The role of arachidonic acid metabolism

Gasomediators, such as nitric oxide, carbon monoxide (CO) and hydrogen sulfide, exert a range of effects on various elements of hemostasis, including the action of blood platelets. CO is known to be produced endogenously, and may provide beneficial effects when present at lower concentrations. In a typical human body, approximately 500 μmoles of CO is generated per day, at a rate of 20 μmoles/h [ [1] Adach W. Olas B. Carbon monoxide and its...