A closer look into NADPH oxidase inhibitors: Validation and insight into their mechanism of action
Abstract
NADPH-oxidases (NOXs) purposefully produce reactive-oxygen-species (ROS) and are found in most kingdoms of life. The seven human NOXs are each characterized by a specific expression profile and a fine regulation to spatio-temporally tune ROS concentration in cells and tissues. One of the best known roles for NOXs is in host protection against pathogens but ROS themselves are important second messengers involved in tissue regeneration and the...
Paper Details
Title
A closer look into NADPH oxidase inhibitors: Validation and insight into their mechanism of action
Published Date
May 1, 2020
Journal
Volume
32
Pages
101466 - 101466
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