Development of a novel murine model of lymphatic metastasis

Volume: 37, Issue: 2, Pages: 247 - 255
Published: Feb 12, 2020
Abstract
Current laboratory models of lymphatic metastasis generally require either genetically modified animals or are technically challenging. Herein, we have developed a robust protocol for the induction of intralymphatic metastasis in wild-type mice with reproducible outcomes. To determine an optimal injection quantity and timeline for tumorigenesis, C57Bl/6 mice were injected directly into the mesenteric lymph duct (MLD) with varying numbers of...
Paper Details
Title
Development of a novel murine model of lymphatic metastasis
Published Date
Feb 12, 2020
Volume
37
Issue
2
Pages
247 - 255
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