Optical Control of Cytokine Signaling via Bioinspired, Polymer-Induced Latency

Published: Feb 14, 2020
Abstract
null Cytokine signaling is challenging to study and therapeutically exploit as the effects of these protein are often pleiotropic. A subset of cytokines can, however, exert signal specificity via association with latency-inducing proteins which cage the cytokine until disrupted by discreet biological stimuli. Inspired by this precision, here we describe a strategy for synthetic induction of cytokine latency via modification with photo-labile...
Paper Details
Title
Optical Control of Cytokine Signaling via Bioinspired, Polymer-Induced Latency
Published Date
Feb 14, 2020
Journal
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