An immune-cell signature of bacterial sepsis

Volume: 26, Issue: 3, Pages: 333 - 340
Published: Feb 17, 2020
Abstract
Dysregulation of the immune response to bacterial infection can lead to sepsis, a condition with high mortality. Multiple whole-blood gene-expression studies have defined sepsis-associated molecular signatures, but have not resolved changes in transcriptional states of specific cell types. Here, we used single-cell RNA-sequencing to profile the blood of people with sepsis (n = 29) across three clinical cohorts with corresponding controls...
Paper Details
Title
An immune-cell signature of bacterial sepsis
Published Date
Feb 17, 2020
Volume
26
Issue
3
Pages
333 - 340
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