The role of tissue biopsy as a biomarker in REM sleep behavior disorder
Abstract
Patients with idiopathic REM-sleep behavior disorder (iRBD) are at substantial risk of progressive neurodegenerative disease of α-synuclein pathology. Longitudinal studies have demonstrated that abnormal α-synuclein deposition occurs early in the course of disease and may precede the appearance of motor symptoms by several decades. This provides rationale for the use of a reliable biomarker to both follow disease progression and to assess...
Paper Details
Title
The role of tissue biopsy as a biomarker in REM sleep behavior disorder
Published Date
Jun 1, 2020
Journal
Volume
51
Pages
101283 - 101283
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