Dll4 Suppresses Transcytosis for Arterial Blood-Retinal Barrier Homeostasis
Abstract
Rationale: Central nervous system has low vascular permeability by organizing tight junction (TJ) and limiting endothelial transcytosis. While TJ has long been considered to be responsible for vascular barrier in central nervous system, suppressed transcytosis in endothelial cells is now emerging as a complementary mechanism. Whether transcytosis regulation is independent of TJ and its dysregulation dominantly causes diseases associated with...
Paper Details
Title
Dll4 Suppresses Transcytosis for Arterial Blood-Retinal Barrier Homeostasis
Published Date
Mar 13, 2020
Journal
Volume
126
Issue
6
Pages
767 - 783
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