Immune checkpoint modulation enhances HIV-1 antibody induction

Volume: 11, Issue: 1, Pages: 948
Published: Feb 19, 2020
Abstract
Eliciting protective titers of HIV-1 broadly neutralizing antibodies (bnAbs) is a goal of HIV-1 vaccine development, but current vaccine strategies have yet to induce bnAbs in humans. Many bnAbs isolated from HIV-1-infected individuals are encoded by immunoglobulin gene rearrangments with infrequent naive B cell precursors and with unusual genetic features that may be subject to host regulatory control. Here, we administer antibodies targeting...
Paper Details
Title
Immune checkpoint modulation enhances HIV-1 antibody induction
Published Date
Feb 19, 2020
Volume
11
Issue
1
Pages
948
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.