AMPfret: synthetic nanosensor for cellular energy states

Volume: 48, Issue: 1, Pages: 103 - 111
Published: Feb 3, 2020
Abstract
Cellular energy is a cornerstone of metabolism and is crucial for human health and disease. Knowledge of the cellular energy states and the underlying regulatory mechanisms is therefore key to understanding cell physiology and to design therapeutic interventions. Cellular energy states are characterised by concentration ratios of adenylates, in particular ATP:ADP and ATP:AMP. We applied synthetic biology approaches to design, engineer and...
Paper Details
Title
AMPfret: synthetic nanosensor for cellular energy states
Published Date
Feb 3, 2020
Volume
48
Issue
1
Pages
103 - 111
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