Combination of Preoperative Plasma Fibrinogen and Neutrophil‐to‐Lymphocyte Ratio (the F‐NLR Score) as a Prognostic Marker of Locally Advanced Rectal Cancer Following Preoperative Chemoradiotherapy

Coagulation and inflammation play important roles in tumor progression. This study aimed to explore the prognostic impact of combined analysis of fibrinogen and neutrophil-to-lymphocyte (NLR) ratio (F-NLR score) in locally advanced rectal cancer (LARC) receiving preoperative chemoradiotherapy (pCRT) and radical surgery. Totally 317 patients were included. X-tile analysis was used to determine the optimal cutoff values of preoperative fibrinogen...