Using human genetics to understand the disease impacts of testosterone in men and women
Abstract
Testosterone supplementation is commonly used for its effects on sexual function, bone health and body composition, yet its effects on disease outcomes are unknown. To better understand this, we identified genetic determinants of testosterone levels and related sex hormone traits in 425,097 UK Biobank study participants. Using 2,571 genome-wide significant associations, we demonstrate that the genetic determinants of testosterone levels are...
Paper Details
Title
Using human genetics to understand the disease impacts of testosterone in men and women
Published Date
Feb 10, 2020
Journal
Volume
26
Issue
2
Pages
252 - 258
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