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Schoolchildren thyroid volume in North Macedonia: data from a national survey in an iodine-sufficient country

Published on Feb 4, 2020in Journal of Endocrinological Investigation
路 DOI :10.1007/s40618-020-01189-6
V. Majstorov1
Estimated H-index: 1
,
Daniela Miladinova2
Estimated H-index: 2
+ 6 AuthorsKaranfilski B1
Estimated H-index: 1
Abstract
Purpose North Macedonia is historically iodine deficient, but due to the longstanding and effective preventive measures, it has been considered iodine replete since 2003. The aim of the recent national survey was to re-evaluate iodine status and to measure thyroid volume (TVol) by ultrasound in schoolchildren as a representative of the general population.
  • References (14)
  • Citations (0)
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References14
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#1Zhe MoH-Index: 7
#2Xiaoming LouH-Index: 10
Last. Xiaofeng WangH-Index: 9
view all 7 authors...
Objective. Thyroid volume measured by ultrasound to define goiter needs reliable local thyroid volume reference from iodine-sufficient populations. The aim of this study is to explore the reference interval for normal thyroid volume in schoolchildren aged 8鈥10 years from Zhejiang Province, China. Methods. A probability-proportionate-to-size sampling method was applied to select a representative sample of 1213 children aged 8鈥10 years in Zhejiang Province to detect the thyroid volume, salt iodine...
7 CitationsSource
#1Saeed Kalantari (University of Gilan)H-Index: 3
#2Masrur Vahabi Moghadam (University of Gilan)H-Index: 1
Background: Few studies have shown the limitation of the World Health Organization (WHO)/ International Council for the Control of Iodine Deficiency (ICCIDD)-adopted thyroid gland volume references as universal normative values for thyroid gland volume. So we decided to measure thyroid gland volume by sonography in schoolchildren in Rasht, Gilan Province, Iran - Rasht is a metropolitan city on the Caspian Sea coast - and compare them to WHO normative values. Materials and Methods: In a cross-sec...
1 CitationsSource
Introduction: A frequency in excess of 5% of goitre in children is an approved WHO marker of iodine deficiency. As thyroid ultrasound remains the main method of thyroid volume (TV) assessment, the choice of adequate normative values is important for the proper interpretation of epidemiologic data. There is disagreement as to whether local or international normative values should be used. The aim of this study was to establish Polish local TV normative values in children aged 6鈥12 years. Material...
12 Citations
#1J. BrunnH-Index: 2
#2U. BlockH-Index: 2
Last. Peter Christian ScribaH-Index: 28
view all 6 authors...
355 CitationsSource
#1P. AndermannH-Index: 3
#2S. Schl枚glH-Index: 4
Last. Chr. ReinersH-Index: 7
view all 6 authors...
Thyroid volume measurement by ultrasonography (US) is essential in numerous clinical diagnostic and therapeutic fields. While known to be limited, the accuracy and precision of two-dimensional (2D) US thyroid volume measurement have not been thoroughly characterized. Objective: We sought to assess the intra- and interobserver variability, accuracy and precision of thyroid volume determination by conventional 2D US in healthy adults using reference volumes determined by three-dimensional (3D) US....
30 Citations
#1P. AndermannH-Index: 3
#2S. Schl枚glH-Index: 4
Last. Chr. ReinersH-Index: 7
view all 6 authors...
Thyroid volume measurement by ultrasonography (US) is essential in numerous clinical diagnostic and therapeutic fields. While known to be limited, the accuracy and precision of two-dimensional (2D) US thyroid volume measurement have not been thoroughly characterized. Objective: We sought to assess the intra- and interobserver variability, accuracy and precision of thyroid volume determination by conventional 2D US in healthy adults using reference volumes determined by three-dimensional (3D) US....
33 CitationsSource
Background: Goiter prevalence in school-age children is an indicator of the severity of iodine deficiency disorders (IDDs) in a population. In areas of mild-to-moderate IDDs, measurement of thyroid volume (Tvol) by ultrasound is preferable to palpation for grading goiter, but interpretation requires reference criteria from iodine-sufficient children. Objective: The study aim was to establish international reference values for Tvol by ultrasound in 6鈥12-y-old children that could be used to define...
167 CitationsSource
#2C. Brook MaxwellH-Index: 1
Last. Joseph G. HollowellH-Index: 7
view all 7 authors...
Urinary iodine (UI) concentrations directly reflect dietary iodine intake and consequently test biochemical assessment of the iodine status worldwide (1). The Iodine Laboratory of the Division of Laboratory Sciences at the National Center for Environmental Health, CDC, measured the UI content of specimens as part of the National Health and Nutrition Examination Survey (NHANES) 2000 and will measure UI in the US population through future NHANES analyses, using inductively coupled plasma mass spec...
61 CitationsSource
A national survey conducted in 1995-96 showed that mild to moderate iodine deficiency existed in Macedonia (median urinary iodine [UI] concentration 117 渭g/l). it was concluded that a new legal regulation should be introduced concerning the iodination of table salt for human consumption. The iodine level was recommended to be 20-30 mg/kg salt, exclusively in the form of the more stable potassium iodate. The new regulations were instituted and became effective in October, 1999. National surveys p...
2 CitationsSource
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