Context-Dependent Pharmacological Effects of Metformin on the Immune System

Volume: 41, Issue: 3, Pages: 162 - 171
Published: Mar 1, 2020
Abstract
Metformin is used for the treatment of type 2 diabetes mellitus and has shown therapeutic effects in preclinical models of other pathologies, such as cancer and autoimmune diseases. The antitumor activity of metformin is due, in part, to immunostimulatory effects. In the context of other pathologies, such as autoimmune or inflammatory diseases, metformin has immunosuppressive effects. There is evidence that the immunostimulatory effects of...
Paper Details
Title
Context-Dependent Pharmacological Effects of Metformin on the Immune System
Published Date
Mar 1, 2020
Volume
41
Issue
3
Pages
162 - 171
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