The landscape of gene mutations in cirrhosis and hepatocellular carcinoma.
Abstract
Chronic liver disease and primary liver cancer are a massive global problem, with a future increase in incidences predicted. The most prevalent form of primary liver cancer, hepatocellular carcinoma, occurs after years of chronic liver disease. Mutations in the genome are a causative and defining feature of all cancers. Chronic liver disease, mostly at the cirrhotic stage, causes the accumulation of progressive mutations which can drive cancer...
Paper Details
Title
The landscape of gene mutations in cirrhosis and hepatocellular carcinoma.
Published Date
May 1, 2020
Journal
Volume
72
Issue
5
Pages
990 - 1002
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Notes
History