The Repertoire of Mutational Signatures in Human Cancer

Nature64.80
Volume: 578, Issue: 7793, Pages: 94 - 101
Published: Feb 5, 2020
Abstract
Somatic mutations in cancer genomes are caused by multiple mutational processes, each of which generates a characteristic mutational signature1. Here, as part of the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium2 of the International Cancer Genome Consortium (ICGC) and The Cancer Genome Atlas (TCGA), we characterized mutational signatures using 84,729,690 somatic mutations from 4,645 whole-genome and 19,184 exome sequences that...
Paper Details
Title
The Repertoire of Mutational Signatures in Human Cancer
Published Date
Feb 5, 2020
Journal
Volume
578
Issue
7793
Pages
94 - 101
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