AIM2 promotes the development of non-small cell lung cancer by modulating mitochondrial dynamics

Volume: 39, Issue: 13, Pages: 2707 - 2723
Published: Jan 31, 2020
Abstract
Mitochondrial fusion and fission dynamics fine-tune cellular calcium homeostasis, ATP production capacity and ROS production and play important roles in cell proliferation and migration. Dysregulated mitochondrial dynamics is closely related to tumor development, but the mechanism of mitochondrial dynamics dysregulation and its role in the development of lung cancer remains unclear. Here, we demonstrate that the DNA sensor protein absent in...
Paper Details
Title
AIM2 promotes the development of non-small cell lung cancer by modulating mitochondrial dynamics
Published Date
Jan 31, 2020
Journal
Volume
39
Issue
13
Pages
2707 - 2723
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