Increased nuclear permeability is a driver for age-related motoneuron loss

Volume: 42, Issue: 3, Pages: 833 - 847
Published: Jan 30, 2020
Abstract
Sarcopenia is the loss of skeletal muscle mass with age, the precise cause of which remains unclear. Several studies have shown that sarcopenia is at least partly driven by denervation which, in turn, is related to loss of motor nerve cells. Recent data suggests degradation of the nucleocytoplasmic barrier and nuclear envelope transport process are contributors to nerve loss in a number of neurodegenerative diseases. Having recently shown that...
Paper Details
Title
Increased nuclear permeability is a driver for age-related motoneuron loss
Published Date
Jan 30, 2020
Volume
42
Issue
3
Pages
833 - 847
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