Genetic Heritability of Pigmentary Glaucoma and Associations With Other Eye Phenotypes

Importance

Mechanisms behind pigmentary glaucoma, a form of early-onset glaucoma that may potentially lead to severe visual impairment or blindness, are poorly understood.

Objective

To calculate the single-nucleotide polymorphism (SNP) heritability of pigmentary glaucoma and identify genetic associations with the disease.

Design, Setting and Participants

This genome-wide association study included affected individuals...