Original paper
Lithium prevents grey matter atrophy in patients with bipolar disorder: an international multicenter study
Abstract
Background Lithium (Li) is the gold standard treatment for bipolar disorder (BD). However, its mechanisms of action remain unknown but include neurotrophic effects. We here investigated the influence of Li on cortical and local grey matter (GM) volumes in a large international sample of patients with BD and healthy controls (HC). Methods We analyzed high-resolution T1-weighted structural magnetic resonance imaging scans of 271 patients with BD...
Paper Details
Title
Lithium prevents grey matter atrophy in patients with bipolar disorder: an international multicenter study
Published Date
Jan 27, 2020
Journal
Volume
51
Issue
7
Pages
1201 - 1210
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Notes
History