SIRT6 is a DNA double-strand break sensor

eLife7.70
Volume: 9
Published: Jan 29, 2020
Abstract
DNA is a double-stranded molecule in which the two strands run in opposite directions, like the lanes on a two-lane road. Also like a road, DNA can be damaged by use and adverse conditions. Double-strand breaks – where both strands of DNA snap at once – are the most dangerous type of DNA damage, so cells have systems in place to rapidly detect and repair this kind of damage. There are three confirmed sensors for double-strand break in human...
Paper Details
Title
SIRT6 is a DNA double-strand break sensor
Published Date
Jan 29, 2020
Journal
Volume
9
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