A Step-by-Step Protocol for Optogenetic Kindling
Abstract
Electrical kindling, repeated brain stimulation eventually resulting in seizures, is widely used as an animal model of epileptogenesis and epilepsy. However, the stimulation electrode used for electric kindling targets unknown neuronal populations and may introduce tissue damage and inflammation. Optogenetics can be used to circumvent these shortcomings by permitting millisecond control of activity in genetically defined neurons without gross...
Paper Details
Title
A Step-by-Step Protocol for Optogenetic Kindling
Published Date
Jan 29, 2020
Journal
Volume
14
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