Luminal Plugging on Chest CT Scan

Mucous exudates occluding the lumen of small airways are associated with reduced lung function and mortality in subjects with COPD; however, luminal plugs in large airways have not been widely studied. We aimed to examine the associations of chest CT scan-identified luminal plugging with lung function, health-related quality of life, and COPD phenotypes.We randomly selected 100 smokers without COPD and 400 smokers with COPD from the COPDGene...