Development of a Uricase-Free Colorimetric Biosensor for Uric Acid Based on PPy-Coated Polyoxometalate-Encapsulated Fourfold Helical Metal–Organic Frameworks

Developing a new cost-effective and reliable approach used for the detection of uric acid (UA) with no requirement of uricase is still very challenging. Herein, an easily realized, cost-effective, and uricase-free approach is reported for selective colorimetric biosensing of UA utilizing polypyrrole (PPy)-coated polyoxometalate-encapsulated fourfold helical metal–organic frameworks Ag5[bimt]2[PMo12O40]·2H2O (Ag5PMo12) as a monolithic peroxidase...