Krebs Cycle Reborn in Macrophage Immunometabolism
Abstract
A striking change has happened in the field of immunology whereby specific metabolic processes have been shown to be a critical determinant of immune cell activation. Multiple immune receptor types rewire metabolic pathways as a key part of how they promote effector functions. Perhaps surprisingly for immunologists, the Krebs cycle has emerged as the central immunometabolic hub of the macrophage. During proinflammatory macrophage activation,...
Paper Details
Title
Krebs Cycle Reborn in Macrophage Immunometabolism
Published Date
Apr 26, 2020
Journal
Volume
38
Issue
1
Pages
289 - 313
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