Physical Principles Underlying the Complex Biology of Intracellular Phase Transitions
Abstract
Many biomolecular condensates appear to form via spontaneous or driven processes that have the hallmarks of intracellular phase transitions. This suggests that a common underlying physical framework might govern the formation of functionally and compositionally unrelated biomolecular condensates. In this review, we summarize recent work that leverages a stickers-and-spacers framework adapted from the field of associative polymers for...
Paper Details
Title
Physical Principles Underlying the Complex Biology of Intracellular Phase Transitions
Published Date
May 6, 2020
Journal
Volume
49
Issue
1
Pages
107 - 133
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