Hepatitis C Virus p7 Induces Membrane Permeabilization by Interacting with Phosphatidylserine

Volume: 21, Issue: 3, Pages: 897 - 897
Published: Jan 30, 2020
Abstract
Hepatitis C virus (HCV) p7 is known to be a nonselective cation channel for HCV maturation. Because the interaction of HCV proteins with host lipids in the endoplasmic reticulum membrane is crucial for the budding process, the identification of p7–lipid interactions could be important for understanding the HCV life cycle. Here, we report that p7 interacts with phosphatidylserine (PS) to induce membrane permeabilization. The interaction of p7...
Paper Details
Title
Hepatitis C Virus p7 Induces Membrane Permeabilization by Interacting with Phosphatidylserine
Published Date
Jan 30, 2020
Volume
21
Issue
3
Pages
897 - 897
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