Prominent White Matter Involvement in Multiple System Atrophy of Cerebellar Type

Background Sporadic degenerative ataxia patients fall into 2 major groups: multiple system atrophy with predominant cerebellar ataxia (MSA‐C) and sporadic adult‐onset ataxia (SAOA). Both groups have cerebellar volume loss, but little is known about the differential involvement of gray and white matter in MSA‐C when compared with SAOA. Objectives The objective of this study was to identify structural differences of brain gray and white matter...