Comparison of aggregate and individual participant data approaches to meta-analysis of randomised trials: An observational study
Abstract
Background It remains unclear when standard systematic reviews and meta-analyses that rely on published aggregate data (AD) can provide robust clinical conclusions. We aimed to compare the results from a large cohort of systematic reviews and meta-analyses based on individual participant data (IPD) with meta-analyses of published AD, to establish when the latter are most likely to be reliable and when the IPD approach might be required. Methods...
Paper Details
Title
Comparison of aggregate and individual participant data approaches to meta-analysis of randomised trials: An observational study
Published Date
Jan 31, 2020
Journal
Volume
17
Issue
1
Pages
e1003019 - e1003019
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