Original paper

Rapid Postnatal Upregulation of Intestinal Farnesoid X Receptor-Fibroblast Growth Factor 19 Signaling in Premature Pigs

Volume: 70, Issue: 5
Published: May 1, 2020
Abstract
Objectives: Bile acid (BA) homeostasis is regulated by intestinal cellular signaling involving the farnesoid X receptor (FXR) and fibroblast growth factor 19 (FGF19) secretion. Using preterm and term pigs as a model, we examined postnatal changes in expression of the FXR‐FGF19 axis that is poorly characterized in human infants. Methods: Pigs delivered by caesarean section at 10‐day preterm and near full term (115‐day gestation) were fitted with...
Paper Details
Title
Rapid Postnatal Upregulation of Intestinal Farnesoid X Receptor-Fibroblast Growth Factor 19 Signaling in Premature Pigs
Published Date
May 1, 2020
Volume
70
Issue
5
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