Peripheral innate immune and bacterial signals relate to clinical heterogeneity in Parkinson’s disease
Abstract
The innate immune system is implicated in Parkinson's disease (PD), but peripheral in-vivo clinical evidence of the components and driving mechanisms involved and their relationship with clinical heterogeneity and progression to dementia remain poorly explored. We examined changes in peripheral innate immune-related markers in PD cases (n = 41) stratified according to risk of developing early dementia. 'Higher Risk'(HR) (n = 23) and 'Lower Risk'...
Paper Details
Title
Peripheral innate immune and bacterial signals relate to clinical heterogeneity in Parkinson’s disease
Published Date
Jul 1, 2020
Journal
Volume
87
Pages
473 - 488
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