Epithelial–Neuronal Communication in the Colon: Implications for Visceral Pain
Abstract
Visceral hypersensitivity and pain result, at least in part, from increased excitability of primary afferents that innervate the colon. In addition to intrinsic changes in these neurons, emerging evidence indicates that changes in lining epithelial cells may also contribute to increased excitability. Here we review recent studies on how colon epithelial cells communicate directly with colon afferents. Specifically, anatomical studies revealed...
Paper Details
Title
Epithelial–Neuronal Communication in the Colon: Implications for Visceral Pain
Published Date
Mar 1, 2020
Journal
Volume
43
Issue
3
Pages
170 - 181
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