cis-regulatory variation modulates susceptibility to enteric infection in the Drosophila genetic reference panel
Abstract
Background Resistance to enteric pathogens is a complex trait at the crossroads of multiple biological processes. We have previously shown in the Drosophila Genetic Reference Panel (DGRP) that resistance to infection is highly heritable, but our understanding of how the effects of genetic variants affect different molecular mechanisms to determine gut immunocompetence is still limited. Results To address this, we perform a systems genetics...
Paper Details
Title
cis-regulatory variation modulates susceptibility to enteric infection in the Drosophila genetic reference panel
Published Date
Jan 17, 2020
Journal
Volume
21
Issue
1
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