Review paper
Molecular mechanisms in SUMO conjugation
Abstract
The small ubiquitin-like modifier (SUMO) is a post-translational modifier that can regulate the function of hundreds of proteins inside the cell. SUMO belongs to the ubiquitin-like family of proteins that can be attached to target proteins by a dedicated enzymatic cascade pathway formed by E1, E2 and E3 enzymes. SUMOylation is involved in many cellular pathways, having in most instances essential roles for their correct function. In this review,...
Paper Details
Title
Molecular mechanisms in SUMO conjugation
Published Date
Dec 24, 2019
Volume
48
Issue
1
Pages
123 - 135
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