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Relationships between Dietary Inflammatory Index score and markers of inflammation and WNT signalling in the healthy colorectal mucosa

Published on Jan 22, 2020
· DOI :10.1017/S002966511900137X
F.C. Malcomson , F. Malcomson1
Estimated H-index: 1
(Newcastle University)
+ 10 AuthorsD. M. Bradburn13
Estimated H-index: 13
Abstract
  • References (3)
  • Citations (0)
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References3
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#1Lavanya Moparthi (Linköping University)H-Index: 1
#2Stefan Koch (Linköping University)H-Index: 18
Abstract Chronic inflammatory bowel diseases, including Crohn's disease and ulcerative colitis, are a major health burden worldwide. Numerous conserved signaling pathways control tissue injury and repair during colitis, but owing to the complexity of the inflammatory process, their individual contribution remains poorly understood. A key regulatory pathway in the intestinal mucosa is Wnt/β-catenin signaling, which acts as the central organizer of epithelial stem cell identity and maintenance. Ap...
4 CitationsSource
#1Nitin ShivappaH-Index: 34
#2Justyna GodosH-Index: 20
Last. Giuseppe GrossoH-Index: 41
view all 7 authors...
Diet and chronic inflammation of the colon have been suggested to be risk factors in the development of colorectal cancer (CRC). The possible link between inflammatory potential of diet, measured through the Dietary Inflammatory Index (DII®), and CRC has been investigated in several populations across the world. The aim of this study was to conduct a meta-analysis on studies exploring this association. Data from nine studies were eligible, of which five were case-control and four were cohort stu...
34 CitationsSource
#1Nitin Shivappa (USC: University of South Carolina)H-Index: 34
#2Susan E. Steck (USC: University of South Carolina)H-Index: 35
Last. James R. Hebert (USC: University of South Carolina)H-Index: 59
view all 5 authors...
Objective To design and develop a literature-derived, population-based dietary inflammatory index (DII) to compare diverse populations on the inflammatory potential of their diets. Design Peer-reviewed primary research articles published through December 2010 on the effect of diet on inflammation were screened for possible inclusion in the DII scoring algorithm. Qualifying articles were scored according to whether each dietary parameter increased (+1), decreased (−1) or had no (0) effect on six ...
393 CitationsSource
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