CpG-island-based annotation and analysis of human housekeeping genes
Abstract
By reviewing previous CpG-related studies, we consider that the transcription regulation of about half of the human genes, mostly housekeeping (HK) genes, involves CpG islands (CGIs), their methylation states, CpG spacing and other chromosomal parameters. However, the precise CGI definition and positioning of CGIs within gene structures, as well as specific CGI-associated regulatory mechanisms, all remain to be explained at individual gene and...
Paper Details
Title
CpG-island-based annotation and analysis of human housekeeping genes
Published Date
Jan 25, 2020
Journal
Volume
22
Issue
1
Pages
515 - 525
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