Integrated, multicohort analysis reveals unified signature of systemic lupus erythematosus
Abstract
Systemic lupus erythematosus (SLE) is a complex autoimmune disease that follows an unpredictable disease course and affects multiple organs and tissues. We performed an integrated, multicohort analysis of 7,471 transcriptomic profiles from 40 independent studies to identify robust gene expression changes associated with SLE. We identified a 93-gene signature (SLE MetaSignature) that is differentially expressed in the blood of patients with SLE...
Paper Details
Title
Integrated, multicohort analysis reveals unified signature of systemic lupus erythematosus
Published Date
Feb 27, 2020
Journal
Volume
5
Issue
4
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