Original paper
Metachromatic leukodystrophy and transplantation: remyelination, no cross‐correction
Volume: 7, Issue: 2, Pages: 169 - 180
Published: Jan 22, 2020
Abstract
In metachromatic leukodystrophy, a lysosomal storage disorder due to decreased arylsulfatase A activity, hematopoietic stem cell transplantation may stop brain demyelination and allow remyelination, thereby halting white matter degeneration. This is the first study to define the effects and therapeutic mechanisms of hematopoietic stem cell transplantation on brain tissue of transplanted metachromatic leukodystrophy patients.Autopsy brain tissue...
Paper Details
Title
Metachromatic leukodystrophy and transplantation: remyelination, no cross‐correction
Published Date
Jan 22, 2020
Volume
7
Issue
2
Pages
169 - 180
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Notes
History