Leishmaniadual‐specificity tyrosine‐regulated kinase 1 (DYRK1) is required for sustainingLeishmaniastationary phase phenotype

Volume: 113, Issue: 5, Pages: 983 - 1002
Published: Feb 11, 2020
Abstract
Although the multiplicative and growth‐arrested states play key roles in Leishmania development, the regulators of these transitions are largely unknown. In an attempt to gain a better understanding of these processes, we characterised one member of a family of protein kinases with dual specificity, Lin DYRK1, which acts as a stasis regulator in other organisms. Lin DYRK1 overexpressing parasites displayed a decrease in proliferation and in cell...
Paper Details
Title
Leishmaniadual‐specificity tyrosine‐regulated kinase 1 (DYRK1) is required for sustainingLeishmaniastationary phase phenotype
Published Date
Feb 11, 2020
Volume
113
Issue
5
Pages
983 - 1002
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