Enhanced in vivo mucosal interferon and chemokine responses to a single stranded RNA analogue (R848) in participants with asthma
Published: Mar 7, 2019
Abstract
Background: Viruses play an important role in asthma exacerbations and are detected by Toll-like receptors (TLRs). Better characterization of mucosal innate immunity to viral triggers may help understand dysregulated host responses in asthma. Aims & Objectives: A synthetic analogue of single-stranded RNA (ssRNA) and TLR7/8 agonist resiquimod (R848) was administered in vivo to study the effect of allergy and asthma on nasal...
Paper Details
Title
Enhanced in vivo mucosal interferon and chemokine responses to a single stranded RNA analogue (R848) in participants with asthma
Published Date
Mar 7, 2019
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