Is there a relationship between low-grade systemic inflammation and cognition in healthy people aged 60–75 years?

Masoumeh Tangestani Fard; Lachlan Cribb; Karen Nolidin; Karen Savage; Keith Wesnes; Con Stough

doi:https://doi.org/10.1016/j.bbr.2020.112502

doi.org/10.1016/j.bbr.2020.112502

Is there a relationship between low-grade systemic inflammation and cognition in healthy people aged 60–75 years?

Masoumeh Tangestani Fard

3

,

Lachlan Cribb

10

,

..., Con Stough

52

Behavioural Brain Research2.70

Volume: 383, Pages: 112502 - 112502

Published: Apr 1, 2020

Abstract

Although inflammation has been associated with cognitive impairment in dementia, less is known about its role in the cognition of middle to older aged healthy people. This study utilised baseline data from the Australian Research Council Longevity Intervention (ARCLI) trial to investigate the relationship between markers of systemic inflammation (TNF-α, IL-6, IL-1β, INF-γ, IL-2, IL-4, IL-10 and hsCRP) and cognitive function in 286 healthy...