Integration of epidemiologic, pharmacologic, genetic and gut microbiome data in a drug–metabolite atlas
Abstract
Progress in high-throughput metabolic profiling provides unprecedented opportunities to obtain insights into the effects of drugs on human metabolism. The Biobanking BioMolecular Research Infrastructure of the Netherlands has constructed an atlas of drug-metabolite associations for 87 commonly prescribed drugs and 150 clinically relevant plasma-based metabolites assessed by proton nuclear magnetic resonance. The atlas includes a meta-analysis of...
Paper Details
Title
Integration of epidemiologic, pharmacologic, genetic and gut microbiome data in a drug–metabolite atlas
Published Date
Jan 1, 2020
Journal
Volume
26
Issue
1
Pages
110 - 117
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Notes
History