BGP‐15: A potential therapeutic agent for critical illness myopathy

In the current issue of Acta Physiologica, Larsson and colleagues examined the effect of chaperone co-inducer BGP-15 on impaired contractile function of the slow-twitch soleus muscles in a rat intensive care unit (ICU) model.1 They found that BGP-15 improves myofibrillar function in the soleus muscle after 5 days exposure to the ICU condition, which is accompanied by improved mitochondrial morphology/biogenesis and reduced oxidative...