FOXO3a‑SIRT6 axis suppresses aerobic glycolysis in melanoma

Published: Jan 17, 2020
Abstract
Melanoma, the most aggressive human skin tumor, has a very short survival time, and there are currently no effective treatments. Alterations in cell metabolism, such as enhanced aerobic glycolysis, have been identified as hallmarks of cancer cells. In the present study, bioinformatics studies using online databases revealed that FOXO3a expression was lower in melanoma tissues compared with normal tissues and nevus. Additionally, Kaplan-Meier...
Paper Details
Title
FOXO3a‑SIRT6 axis suppresses aerobic glycolysis in melanoma
Published Date
Jan 17, 2020
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