Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes.

Volume: 52, Issue: 1, Pages: 56 - 73
Published: Jan 7, 2020
Abstract
Genome-wide association studies have identified breast cancer risk variants in over 150 genomic regions, but the mechanisms underlying risk remain largely unknown. These regions were explored by combining association analysis with in silico genomic feature annotations. We defined 205 independent risk-associated signals with the set of credible causal variants in each one. In parallel, we used a Bayesian approach (PAINTOR) that combines genetic...
Paper Details
Title
Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes.
Published Date
Jan 7, 2020
Volume
52
Issue
1
Pages
56 - 73
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.