Non-invasive Molecular Detection of Minimal Residual Disease in Papillary Thyroid Cancer Patients
Abstract
Background: Papillary thyroid cancer (PTC) is the most common type of thyroid malignancy. Serum thyroglobulin (Tg) levels are used to monitor PTC treatment response and recurrences however, in about 25% of the cases the sensitivity of this method is compromised due to either the presence of neutralizing anti-Tg antibodies (TgAb) or the absence of Tg in less differentiated tumors. Up to 80% of PTC tumors harbor the c.1799T>A hotspot mutation in...
Paper Details
Title
Non-invasive Molecular Detection of Minimal Residual Disease in Papillary Thyroid Cancer Patients
Published Date
Jan 10, 2020
Journal
Volume
9
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